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I'm starting to get more and more fonts built up in my library. Believe it's time to outgrow Font Book and look for something more professional.
I'm on Snow Leopard (Mac) and the tools I use are Illustrator CS4, Photoshop CS4 and a lot of Fireworks CS4.
What I'm looking for specifically is a font management application that allows for auto activation for any program that I use on my system. For example, if I open up a project in Fireworks, or even Microsoft Word or Excel, and have used a font that is no longer activated as of right now that it will automatically activate the font for the time being just for that particular program.