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A humanist sans serif design that was the product of the collaboration between Robert Slimbach and Carol Twomblywith Fred Brady & Christopher Slye. Myriad was orignally released in 1992.
A prominent use of this typeface is by Apple (it is actually Myriad Pro Semibold).

Discussion:
Adrian Frutiger on Myriad
Additional Articles:
Wikipedia: Myriad